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Expert care for a wide range of skin conditions, ensuring healthy, radiant skin.


Lesions & Bumps


Comprehensive care for skin lesions and bumps, promoting clear and healthy skin.


Lifting & Tightening


Advanced treatments to lift and lighten the skin, enhancing firmness and brightness.


Rejuvenation


Revitalize your skin with advanced treatments designed to restore a youthful glow.


Skin Treatments


Effective solutions for a variety of skin concerns, promoting clear and healthy skin.


Wellness


Holistic skincare approaches to support overall skin health and well-being.


Advanced, non-invasive treatments to rejuvenate your appearance without surgery.


Body Treatments


Transformative, non-invasive treatments to sculpt and tone your body effortlessly.


Facial Treatments


Rejuvenating facial treatments to refresh and enhance your natural radiance.


Hair Treatments


Advanced treatments to restore hair vitality and promote healthy growth.


Injectables


Minimally invasive injectables to smooth wrinkles and enhance facial contours.


Precision cosmetic surgery tailored to enhance and refine your natural beauty.


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Expertly performed body surgeries to reshape, contour, and enhance your physique.


Breast Surgery


Specialized breast surgeries to enhance shape, size, and symmetry for a natural look.


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Advanced procedures designed to enhance male aesthetics and address intimate concerns.


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Tailored surgical solutions to enhance feminine aesthetics and improve intimate well-being.


Facial Surgery


Precision facial surgeries to refine features and achieve natural, balanced results.


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Advanced fat transfer and removal techniques to sculpt and enhance your body’s contours.


Comprehensive solutions to address a range of body concerns, from stubborn fat to skin laxity.


Breasts


Tailored solutions for breast concerns, including size, shape, and symmetry.


Other Areas


Targeted solutions for stubborn areas of the body, tailored to your unique needs.


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Specialized treatments to enhance body volume and improve overall contour for a balanced silhouette.


Holistic care focused on improving overall health and well-being for a balanced lifestyle.


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Comprehensive care to support digestive health and improve overall well-being.


Energy & Immunity


Holistic approaches to boost energy levels and strengthen your immune system for optimal health.


General Health


Personalized strategies to maintain and enhance your overall health and vitality.


Expert care for a wide variety of skin and facial concerns, promoting a healthy, glowing complexion.


Ageing Signs


Expert treatments to minimize ageing signs, rejuvenating your skin for a youthful glow.


Skin Texture & Tone


Advanced treatments to improve skin texture and even out tone for a smoother, radiant complexion.


Specific Areas


Targeted treatments to address skin concerns in specific facial areas for balanced, refined results.


Volume & Contouring


Tailored solutions to restore facial volume and enhance natural contours for a more youthful appearance.



When a friend uses your referral code, they'll get £50 off their first treatment, and you'll get £50 off your next one.


The more friends you invite, the more you earn.


The Benefits of Using Polynucleotide Under Eyes: A Comprehensive Guide


Quick Summary


Polynucleotide under eye treatment is a non-invasive injectable that gently improves your under eye area. It is a gentle treatment that helps your skin repair itself by boosting collagen, hydration, and elasticity. This makes it ideal if you have dark circles, fine lines, or eyes that look tired. Results develop slowly over a few weeks and last between 6 to 12 months, with very little downtime.


 


Polynucleotides are tiny fragments of DNA that are gently cleansed and used for skin treatments to help regenerate and repair your skin. They are from salmon or trout DNA because it is very compatible with human tissue and very well tolerated.


Related read:


 


There are different under eye treatments available, and these is how they differ:


 


One of the reasons polynucleotides are becoming popular in London clinics is because it does work wonders on your skin.


 


The treatment involves injecting a small amount of polynucleotide solution just under the skin in the under eye area. This is done using a very fine needle to keep the process as gentle as possible.


The whole procedure will just take around 20 to 30 minutes, and numbing cream is used to keep you comfortable.


 


After injecting polynucleotides, they start working beneath the surface in a few ways:


This is why polynucleotides are often prescribed as a regenerative treatment.


 


Polynucleotides help improve the thickness and quality of your skin. As the skin becomes healthier, it can make the area look brighter.


One reason why the under eye looks dull is because of dehydration. Polynucleotides help your skin hold moisture more effectively.


This treatment boosts collagen and elastin that helps soften facial lines slowly and result in smoother skin.


Polynucleotides have anti-inflammatory properties that help calm your skin and reduce slight puffiness.


One of the biggest advantages of this treatment is improving your skin over time. Your results look more natural and continue to get better even weeks after the treatment.


 


It helps to understand what real results look like for any treatment you are considering.


 


Most people will need more than just one session.


This gives your skin time to respond and slowly improve.


 


Effective & professional doctor-led Benefits of Using Polynucleotide Under Eyes at our central London clinic


 


Results do not instantly happen, here is the timeline:


 


You will notice:


 


 


Combination of these are sometimes recommended to the best overall results, treating both skin quality and volume.


Related read:


 


During the consultation, your practitioner will:


This is also the chance to ask all your questions and feel comfortable before going ahead.


 


The process is quite simple:


Related read:


 


Most people describe the sensation as a slight pinch or pressure. It is not usually painful, especially when numbing cream takes effect.


 


After the treatment, you may notice:


These are temporary and settle within a few days.


 


Simple aftercare tips include:


Following a consistent under eye skin routine can help you maintain your results for longer periods of time.


Most people enjoy the results around 6 to 12 months, depending on your lifestyle, skin type, and how well you maintain your skin.


 


Typical price in the UK ranges from:


Prices depend on the clinic location, practitioner experience, and product used.


Related read:


 


Look to polynucleotide as an investment in your skin. This treatment improves your skin over time, it means fewer treatments over time.


 


Polynucleotide injections are safe especially when done by an expert professional.


 


These are normal and usually settle within a few days.


 


This may not be suitable for your if you:


Always choose a reputable clinic in the UK with experienced professionals.


 


It improves the quality of your under eye skin by boosting collagen, hydration and repair. This reduced dark circles, fine lines, and dull looking eyes.


You may see early improvements within a couple of weeks, full results take around 6 to 8 weeks.


Most people find it manageable. Numbing cream helps to keep you comfortable.


Both treatments target different goals. Polynucleotides improve the quality of the skin, while fillers add volume.


You will need 2 to 3 sessions to start, maintenance sessions every 6 to 9 months.


 


It is worth considering polynucleotides if you want a natural way to freshen up your under eye area. It helps your skin become healthier, smoother, and more hydrated over time.


If you do not want a dramatic change, this treatment is perfect for you. Book a consultation with a qualified practitioner to create a personalised plan for your skin health.


Reserve a polynucleotides appointment


One of our experts will be more than happy to answer any questions you have.



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Melis Mackley


Love this clinic I practically live here


16th June 2026


Jaswinder Marwaha


Had an initial consultation, the staff put you at ease immediately and were very knowledgable. Would recommend to anyone that is thinking about going to a clinic.


16th June 2026


Ah Q


I had a positive experience with Dr Cumbo. This was for a review and procedure. There was close attention to detail provided


13th June 2026


Book Today and Enjoy £50 Off Your First Appointment as a Welcome Gift from Harley Street Skin Clinic


Use code GET50 at checkout. Limited-time only.


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Need to reach us?
Contact or visit our clinic.


We're based in central London at the historic which is only a short 2 minute walk from Regents Park tube station a 10 minute taxi journey to Kings Cross, and St Pancras stations.


We're open Monday - Friday 8am - 8pm, and Saturdays 9am - 5pm, feel free to drop in to talk to a member of our team where they can answer any of your questions.


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The Harley Street Skin Clinic is an award-winning boutique private cosmetic clinic in the heart of London. We offer the most advanced surgical and non surgical techniques in our fully-fitted consulting rooms, state-of-the-art operating theatres and purpose-built aesthetics and laser suite.





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